"Which of the three is the best?" is a question we often receive.
If they could be ranked, all three would not exist side-by-side.
Each addresses a different aspect, so the first step is to determine which aspect your concern falls under.
Please take just one minute to read this.
Divided into Three Aspects
| Aspect Addressed | Timing of Change | Best for Concerns | |
|---|---|---|---|
| Filler | Volume | Immediate | Specific areas are sunken |
| Rejuran | Skin texture and condition | Over multiple sessions | Thin, rough, and sensitive skin |
| Juvelook | Inducing collagen production | Over several weeks | Overall loss of firmness |
It is common for all three aspects to be present on the same face. Therefore, many consultations cannot be resolved with just one approach.

What Filler Does
Filler directly fills in sunken areas by injecting a substance. Since the shape changes the moment it is injected, the change is immediately visible.
However, the layer and amount injected determine the result. Too much can look unnatural, and if the placement is off, the shape may change in an undesired way.

What Rejuran Does
The purpose of Rejuran is not to create volume. It is closer to addressing the condition of the skin itself.
It is a method that involves building up sessions to improve thin, rough skin and skin that easily reddens with irritation. It is not a one-time procedure.

What Juvelook Does
Juvelook stimulates tissues to produce collagen on their own. The injected substance does not immediately become volume; rather, the collagen produced over time acts as volume.
Therefore, the change is not distinct immediately after the procedure and appears gradually over several weeks. If you have an urgent schedule, the timing may not be suitable.

How to Choose
Formulating your concern into a sentence can reveal the aspect it falls under.
"This area is sunken" relates to the volume aspect. "My skin is thin and keeps reddening" relates to the skin texture and condition aspect. "My skin feels generally weak and sagging" is closer to the collagen aspect.
If all three sentences apply, prioritize them. It is often easier to see results by determining which aspect has the greatest impact on your appearance rather than doing everything at once.

Precautions When Combining Procedures
While combining procedures is not inherently problematic, overlapping multiple methods in the same area may lead to excessive volume or an uneven surface.
Additionally, the recovery response may be amplified, causing swelling or bruising to last longer than usual. It is important to consider if this overlaps with your schedule.
If you are curious about the interval for repeated treatments, you can refer to the article explaining what sets the Rejuran interval.

Recovery and Precautions
Swelling, bruising, nodule formation, and erythema may occur, and the degree and duration vary from person to person.
Especially when performing procedures near blood vessels, it is important to precisely control the layer and amount injected.
It is safer to consult with medical staff before the procedure to confirm if the combination is suitable for your condition.

Frequently Asked Questions
How can I summarize it in one sentence?
Filler fills, Rejuran addresses skin condition, and Juvelook stimulates collagen production.
Why do I need repeated treatments?
Rejuran and Juvelook work by building up tissue responses, so a single stimulation often does not achieve the desired goal.
Can I receive all three at once?
It is possible depending on your condition, but overlapping them in the same area can be excessive, so it is better to prioritize and sequence the aspects.
I am concerned about pain.
The degree of pain experienced varies greatly from person to person. If you feel uncomfortable during the procedure, please let us know, and we will adjust the speed and method.
What are the side effects of Filler?
In addition to swelling and bruising, depending on the layer and amount injected, the shape may appear unnatural or a feeling of pressure may remain. Areas around blood vessels require particularly careful approach.
Visit and Consultation Information
O.N Clinic is located near Gangnam Station, making it easily accessible by subway.
To accurately determine which of the three aspects has the greatest impact on your appearance, it is best to assess both your skin and volume condition. For any questions, you can easily inquire via Chat for consultation now.
Author: Dr. Oh Seung-min (Chief Director of O.N Clinic, graduated from Seoul National University College of Medicine, Academic Committee Chairman of the Korean Laser Dermatology and Hair Society). For more details on his background, please refer to Medical Staff Introduction. First published 2026-08-19 / Last reviewed 2026-08-25
This article is for general information purposes only, and suitable treatments and results may vary depending on individual conditions.