Many people ask, "Should I get a Skin Booster or a Toxin for fine lines around the eyes and on the forehead?"
However, what we check first in the examination room is not the name of the procedure, but where those wrinkles originated.
Even if fine lines appear in the same area, if the cause is different, the approach will also differ.
Take just one minute to read this.
Eye Wrinkles: You Must First Distinguish 'This'
Fine lines around the eyes and on the forehead, which appear similar on the surface, actually have different causes for each person.
This is because the degree of skin dryness, skin texture, pore condition, presence of reduced elasticity, and wrinkle depth all vary.
Therefore, even for seemingly similar wrinkles, the appropriate approach may differ.
It's easier to understand if we broadly divide the causes into two.
- Thin, fine wrinkles caused by dry skin and reduced elasticity — Skin Boosters like Rejuran or Retigen, which replenish moisture, regeneration, and elasticity within the skin, may be helpful.
- Wrinkles that form due to muscle movement when making facial expressions — Botulinum Toxin, which directly controls muscle movement, may be more suitable.
If the same procedure is applied to all fine lines without clear criteria, it may not match the cause, making it difficult to feel the expected change.
Therefore, when considering fine line treatments, we recommend checking not only the clinic's location, cost, and downtime, but also whether the procedure is appropriate for the cause of your wrinkles.
This point was also discussed in the same context in Why Treatments Differ According to Wrinkle Type.
Rejuran and Retigen: Which Fine Lines Are They Suitable For?
Rejuran and Retigen are representative Skin Boosters that work by replenishing moisture, regeneration, and elasticity within the skin.
They may be helpful for thin, fine wrinkles caused by dryness or reduced elasticity, and positive effects on skin texture improvement can also be expected.
Both procedures directly affect the internal environment of the skin, but their ingredients and characteristics differ, so the appropriate choice varies depending on the skin condition.
It is best to decide which Skin Booster is more suitable for you after comprehensively checking your skin's dryness, pore condition, and wrinkle depth.
Skin Boosters can be used alone, but if the cause is complex or if reduced elasticity is also present, combining them with other procedures can also be considered.
(※ The effectiveness and response of the procedure may vary depending on the individual's skin condition, and the applicability of the procedure is determined through consultation with medical staff.)
There's a saying that "the more painful Rejuran is, the better," but in the examination room, we first look at whether the wrinkle is of a nature that can be treated with a Skin Booster, rather than the intensity of the pain. If you're curious about the relationship between pain and effectiveness, you can also read Criteria for Checking Rejuran's Effectiveness and Pain Before Treatment.
The difference in ingredients between Rejuran and Retigen alone does not determine the outcome.
Even with the same product, the response varies depending on whether it is designed with the appropriate intensity and frequency for your skin. This part is explained in more detail in Why Rejuran's Effectiveness Varies from Person to Person.
If you have any questions, feel free to ask via Chat for Consultation Now.
If You Also Have Reduced Elasticity, Should You Add Oligio Kiss?
If you are concerned about reduced facial elasticity along with fine lines, instead of approaching it with just one Skin Booster, you might consider combining it with a procedure that can manage skin texture, fine lines, and elasticity together.
A representative example is combining it with Oligio Kiss.
Oligio Kiss is a procedure that delivers high-frequency and ultrasound energy to minute areas to stimulate collagen production, which may help improve skin texture, pores, and subtle changes in elasticity.
By replenishing the skin's moisture and regenerative environment with Rejuran and Retigen, and then refining the skin texture and pores with Oligio Kiss, it may help with comprehensive management.
How Oligio Kiss is differentiated from other Lifting & Tightening procedures is summarized in Why Oligio Kiss and Onda Lifting are Recommended Differently.
However, combination is not always the answer.
Here's how procedures are paired depending on the cause:
| Main Cause | Primary Consideration | Combination Possibility |
|---|---|---|
| Dry, thin fine lines | Rejuran·Retigen Skin Booster | Possible alone |
| Accompanied by texture·pore·elasticity reduction | Skin Booster plus Oligio Kiss | Consider combination |
| Facial muscle movement | Botulinum Toxin | Review combination if causes overlap |
Even with the same procedure, the results vary depending on how the combination and intensity are designed for your skin.
It is helpful to consider the criteria for designing the procedure, rather than just which procedure you receive.
In the Examination Room, We Divide Causes in This Order
In the examination room, when determining the approach for fine lines, we generally follow this sequence:
- First, we distinguish whether the wrinkles are caused by dryness or if facial muscle movement is the primary cause.
- We carefully examine the skin texture, pore condition, and presence of reduced elasticity.
- We design whether to proceed with a single treatment, a combination, and in what order.
Skipping this process and deciding on the procedure name first can lead to lower satisfaction due to a mismatch with the cause.
If you are also concerned about pores, Cases Requiring a Combination of Retigen and Oligio X can also be helpful.
Precautions to Check Before Fine Line Treatment
(※ The effectiveness and response of each procedure, such as Rejuran, Retigen, Oligio Kiss, and Botulinum Toxin, may vary depending on the individual's skin condition.)
Swelling, redness, bruising, or pain may appear at the treatment site, and in the case of Botulinum Toxin, temporary changes in muscle movement may occur.
The applicability and combination of procedures must be determined through consultation with medical staff, and sufficient consultation before the procedure is important.
Since the appropriate procedure varies depending on whether the cause of your wrinkles is dryness or facial muscle movement, identifying the cause comes first.
Practical factors such as cost, downtime, and clinic location are, of course, also important.
However, it is better to prioritize the process of confirming whether the procedure is suitable for your skin condition and the cause of your wrinkles.
We recommend looking at the criteria for designing the procedure rather than just the type of procedure.
If the distinction of the cause feels ambiguous, you can inquire with a photo via Chat for Consultation Now.
Frequently Asked Questions
Can I achieve results for fine lines around the eyes and on the forehead with Skin Boosters alone?
If the fine lines are thin and subtle, caused by dryness or reduced elasticity, Skin Boosters like Rejuran or Retigen may be helpful.
However, if facial muscle movement is the primary cause, Botulinum Toxin may be more suitable than Skin Boosters, and since the approach varies depending on the cause, it is better to consult with medical staff first.
What is the difference between Rejuran and Retigen?
Both procedures are Skin Boosters that replenish the internal environment of the skin, but there are differences in their ingredients and characteristics.
It is best to determine which product is more suitable after comprehensively checking your skin condition and consulting with medical staff.
What combination is good for improving fine lines and reduced elasticity together?
If reduced elasticity is also present, you can consider combining Rejuran and Retigen to replenish the skin's moisture and regenerative environment with a procedure that stimulates collagen production, such as Oligio Kiss.
The appropriate combination varies depending on the individual's skin condition, so it is important to determine the procedure design through consultation with medical staff.
Can there be swelling or reactions after Skin Booster treatment?
Swelling, redness, bruising, or pain may temporarily appear at the treatment site, and reactions may vary depending on the individual's skin condition.
If Botulinum Toxin is combined, temporary changes in muscle movement may occur, so we recommend sufficient consultation with medical staff before the procedure.
What is the first criterion to check when choosing a fine line treatment?
It is important to first understand the cause of your fine lines, rather than just which procedure you receive.
The appropriate procedure varies depending on whether the cause is dryness/reduced elasticity or facial muscle movement, and it is helpful to also check the criteria for designing the procedure.
Recovery and Downtime
Skin Boosters like Rejuran and Retigen, and Botulinum Toxin, are performed with fine injections, so swelling, redness, stinging, or small bruises may appear at the treatment site.
These reactions generally subside within a few days, and there are individual differences depending on the skin condition.
Procedures using high-frequency and ultrasound energy, such as Oligio Kiss, may cause a temporary sensation of heat or redness immediately after, but a return to daily life is generally relatively quick.
Botulinum Toxin may cause temporary changes in muscle movement.
Recovery patterns and duration vary depending on the type, intensity, and area of the procedure, so we recommend confirming the specific progress during consultation with medical staff before the procedure.
How the Cost is Structured
It is difficult to state a single fixed price for fine line treatments.
This is because the structure varies depending on which Skin Booster is used (products like Rejuran, Retigen, etc.), the scope and area of the treatment (around the eyes, forehead, etc.), whether it is combined with other procedures like Oligio Kiss, and whether post-care or additional treatment plans are included.
Therefore, even for procedures with the same name, the information provided may differ depending on the design method.
The exact cost will be provided after checking your skin condition and through consultation. If you have any questions, you can inquire in advance via Chat for Consultation Now.
Visit and Consultation Information
O.N Clinic is conveniently located near Sinnonhyeon and Gangnam Stations, making it easy to access by subway.
You can check in advance whether fine lines around the eyes and on the forehead are due to dryness or facial muscles with photos, so if you organize your questions via Chat for Consultation Now before your visit, the consultation will be much smoother.
If you are curious about how to make a reservation or consult, please feel free to inquire via chat.
Author: Dr. Oh Seung-min (Representative Director of O.N Clinic, graduated from Seoul National University College of Medicine, Academic Committee Chairman of the Korean Laser Dermatology and Hair Society). For detailed history, please refer to Medical Staff Introduction.
First Published: 2026-06-14 / Last Reviewed: 2026-08-15
This article is for general information purposes only, and appropriate treatment and results may vary depending on individual conditions.
