Rejuran Healer: What's the difference and effect? - Dr. Oh Seung-min | Gangnam Seoul, Korea Dermatology Clinic Guide

Hello.

I am Dr. Oh Seung-min, the lead director of O.N Clinic with 17 years of experience. "Isn't salmon injection Rejuran?" "Both are ingredients derived from salmon, so do they have the same effect?" Many people get confused about these points when looking into skin procedures.

This is because if you search online, some places call Rejuran a salmon injection, while others describe PDRN injection as a salmon injection. Just by the name, it might seem like the same procedure. However, in reality, there can be differences in the molecular structure of the ingredients and their intended use, such as PN and PDRN...

It is difficult to consider them the same procedure simply because they are 'derived from salmon'. Even if they are mentioned as ingredients of the same family, the procedure method can vary depending on which product is used and which skin concern is being addressed.

Today, I will explain the difference between the procedure commonly called salmon injection and Rejuran (Healer), and how to distinguish between PN and PDRN. Please focus and read for just 3 minutes. It will help you clarify the parts you were confused about due to the two similar-sounding names. ^^ Salmon Injection Rejuran (Healer), What are the Differences and Effects?

-Written directly by the lead director with 17 years of experience

First, there is something you should know. The commonly used term 'salmon injection' does not refer to a single, precise ingredient name. In fact, in aesthetic procedures, both PN and PDRN-based products, which use DNA components derived from salmon or salmonid fish, are sometimes collectively referred to as 'salmon injection'.

However, PN and PDRN cannot be considered completely identical substances.

PN is often described as a polynucleotide, consisting of relatively long DNA strands, while PDRN is often described as relatively short DNA fragments. (However, the molecular weight criteria for distinguishing PN and PDRN are not completely standardized, and the two terms may be used interchangeably depending on the literature or product.

Therefore, rather than simply distinguishing by name, it is important to check the ingredients and approved indications of the actual product being used.)

The main ingredient of Rejuran (Healer) is PN. In Korea, it is an approved medical device for the temporary improvement of facial wrinkles in adults. On the other hand, PDRN is also a DNA-derived ingredient that has been the subject of various medical studies.

Therefore, simply saying "I got a salmon injection" might make it difficult to know exactly which ingredient was used. If you decide on a procedure based solely on the term salmon injection without checking the product name, you might get confused about whether the product you expected is actually being used.

That's why in such cases, I always recommend checking what product is being used, whether it's PN or PDRN, and what its approved purpose is. This is because not all products called by similar names can be expected to have the same effect.

So, what is Rejuran (Healer) used for? Here, you need to understand the second difference. Salmon Injection Rejuran (Healer), What are the Differences and Effects?

-Written directly by the lead director with 17 years of experience

Some people who are new to Rejuran (Healer) might think it's a similar procedure to filler. Because it's injected directly into the skin, they might think, "Will it add volume if I get it?" However, Rejuran (Healer) and hyaluronic acid fillers, which are used for volume enhancement, differ in their intended use and product characteristics.

Rejuran's main ingredient is PN, and in Korea, it is an approved product for the temporary improvement of facial wrinkles in adults. (While several studies on PN and changes in skin condition have been reported, the subjects, procedure methods, and number of injections differ for each study, so the research results cannot be applied identically to everyone.)

Simply put, it is closer to managing the skin's own condition. Therefore, understanding Rejuran treatment as directly filling in sunken areas for volume, like a filler, is not appropriate. If you are concerned about facial wrinkles, you can consult with medical staff about the applicability of PN-based products after checking your skin condition.

However, it is important here not to proceed with the procedure blindly, thinking "my skin is bad, so I should get Rejuran." You should first determine whether the main problem is dryness, fine wrinkles, skin elasticity, or if volume loss or sagging is also present.

I do not try to solve the problem with Rejuran alone for patients whose main concern is lack of volume or sagging. This is because it is necessary to distinguish between what the procedure can do and what it cannot do. Rejuran (Healer) is not a procedure that directly supplements volume in the same way as a filler...

It is better to understand it as an injectable medical device that uses PN ingredients. But here, another question arises. Why do treatment methods differ even when using the same Rejuran? Salmon Injection Rejuran (Healer), What are the Differences and Effects?

-Written directly by the lead director with 17 years of experience

Many people wonder about this: "If I get the same Rejuran (Healer), won't everyone receive the exact same treatment??" Not necessarily. Injectable procedures, even when using the same product, are not performed in the same way for everyone.

It requires a process of determining where to inject, checking the skin condition, adjusting the injection depth and interval, and deciding the amount to use. Even within the same face, there can be differences in the condition of the skin around the eyes, cheeks, and mouth.

It is not always appropriate to inject in the same way for both areas where wrinkles are prominent and areas where they are not. For example, if a large amount is concentrated in a thin skin area at once, or if it is injected in a way that does not match the skin condition, post-procedure embossing or swelling may be more noticeable.

(Even in studies related to PN procedures, the injection sites and methods differed across studies, and it is still difficult to say that a single standardized procedure method has been established. ^^;)

That's why I believe that in Rejuran procedures, the process of checking the skin condition before the procedure is as important as the product name itself. Rather than simply injecting uniformly across the entire face at regular intervals, I tend to examine the skin condition and the areas of concern for wrinkles separately.

This is because even with the same product, individual skin conditions and treatment plans can differ. Even if it looks like the same Rejuran procedure, the actual procedure process can vary from person to person. That's why I recommend asking, "Which areas should be checked on my skin?" rather than "How many cc of Rejuran should I get?"

Salmon Injection Rejuran (Healer), What are the Differences and Effects?

-Written directly by the lead director with 17 years of experience

Even if the procedure is performed well, the entire process does not end on that day. Procedures that directly inject products into the skin, like Rejuran, may cause injection marks, redness, swelling, or small bumps immediately afterward.

(The degree of reaction and recovery process may vary depending on individual skin condition and injection site.) Therefore, after the procedure, it is important to observe the current skin condition rather than rubbing or irritating the skin excessively.

Especially if your skin is naturally sensitive or prone to inflammation, it is advisable to inform the medical staff about these aspects before the procedure. And if you experience unusual reactions such as prolonged swelling or worsening pain...

It is better to have your condition checked at the medical institution where you received the procedure rather than simply waiting. When planning a Rejuran procedure, I do not decide on the product first. I first check the skin thickness, the location of fine wrinkles, dryness, elasticity, and whether volume loss or sagging is also present, and then determine if Rejuran is actually needed for the skin.

If necessary, I may plan for specific areas, and if I determine that the cause of the skin concern lies elsewhere, I may recommend other methods in conjunction. During consultation, asking, "Is Rejuran suitable for my skin concerns, or is another cause more significant?" is also a good approach.

Even after the procedure, it is necessary to observe how the injection site recovers and whether there are any unusual reactions in the skin condition. This is because I believe that an injection procedure is not simply a matter of choosing a product, but a process of confirming whether it is suitable for the current skin condition and observing the post-procedure reactions. ^^ Salmon Injection Rejuran (Healer), What are the Differences and Effects?

-Written directly by the lead director with 17 years of experience

This concludes the content I prepared for today. I hope this has been a small help to those who were curious about how salmon injection and Rejuran (Healer) differ, and how to distinguish between PN and PDRN. The key is to confirm what ingredients and products are actually used, and what the approved purpose of that product is, rather than just the name 'salmon injection'.

However, if the cause of your skin concern is volume loss or sagging, insisting on Rejuran alone may not be appropriate.

I hope you will first confirm your skin condition and what changes are needed before deciding on a procedure. Thank you for reading until the end today. This has been Dr. Oh Seung-min, lead director of O.N Clinic.

My skin is thin and I have many fine wrinkles. Can I still receive this procedure in such cases?

The possibility of receiving the procedure is not determined solely by having thin skin. Instead, it is crucial to confirm the skin thickness and the location of fine wrinkles, and then adjust the injection depth and amount more precisely.

My face looks sunken. Will Rejuran (Healer) alone fill it up?

If volume loss is the main problem, it may be difficult to achieve the desired change with PN-based procedures like Rejuran. It is advisable to first determine whether the sunkenness is due to skin condition, or if changes in fat, bone structure, or overall volume are also contributing.

Q. Is it normal to have bumps after a Rejuran (Healer) procedure? Immediately after injection, the injection site may temporarily appear raised, or show redness, swelling, or small bumps. However, if the pain or swelling worsens, or if unusual reactions persist, it is advisable to have it checked by medical staff.

My skin is dry. If I only get Rejuran, do I not need to do moisturizing care?

Injection procedures are not a substitute for regular skin care. If your skin is dry, it is advisable to maintain basic skin care such as moisturizing and sun protection.

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