When summer arrives, there's a conversation we hear much more frequently in the consultation room.
Statements like, "My skin feels tight inside but oily on the surface," or "My face is more sensitive than before."
It's a time when the skin barrier can easily be compromised, as we move between air conditioning and outdoor heat several times a day, and UV rays become stronger.
Many people who consider Rejuran start with this very imbalance of oil and moisture.
Take just one minute to read this.


Rejuran is an injection procedure known to help organize the regenerative environment and support the moisture retention of the dermal layer by injecting PDRN, or polynucleotide components, into the skin. However, the degree and duration of perceived change can vary depending on an individual's skin condition, and satisfaction often depends on pain management methods and a treatment plan tailored to the skin.
Why does oil-moisture imbalance occur in summer?
Oil-moisture imbalance is not simply a problem caused by drinking less water.
When the skin barrier weakens, moisture that should be inside easily escapes, and as a compensatory reaction to make up for the lack of moisture, oil production increases excessively, leading to a shiny surface.
This vicious cycle becomes more pronounced when spending the day under air conditioning in summer and then being exposed to heat and UV rays outdoors.
The point where Rejuran receives attention is its focus on addressing the moisture retention environment of the dermal layer itself.
While topical moisturizers soothe the surface, Rejuran approaches by organizing the skin's internal regenerative environment.
Therefore, it can be considered as an option for those who experience recurring sensitivity and troubles every summer.
Of course, not everyone experiences the same changes.
Even with the same treatment, some people may feel an internal surge of moisture relatively quickly, while others may experience slower changes due to various overlapping factors.
The reasons why Rejuran's effects vary from person to person are discussed in more detail in an article explaining the reasons for varying Rejuran effects from a clinical perspective.


Same Rejuran, why does satisfaction vary?
One common pattern observed in the consultation room:
Among those who decided on Rejuran based solely on price or promotions, there are cases where they did not experience the expected changes because the treatment direction did not match their skin condition.
Even with the same Rejuran, the treatment plan should vary depending on skin type, lifestyle, and treatment goals.
Therefore, O.N Clinic examines the skin condition before treatment. The general flow of this check is as follows:
- First, analyze the current skin condition with AI skin measurement.
- Identify the cause of the oil-moisture imbalance.
- Based on the results, the medical staff designs a personalized treatment plan.
- Provide guidance on post-treatment soothing and home care.
What is as important as the number of treatments or cost is the type of consultation that forms the basis of the treatment plan.
The aforementioned differences in satisfaction are often linked to whether the treatment was designed after a thorough examination of the skin condition.
If you are considering Rejuran, we recommend confirming the direction with a 1:1 consultation with the medical staff before the treatment.
If you are curious whether Rejuran treatment is suitable for your skin, you can comfortably ask by chatting now for a consultation.


Are you hesitating due to pain?
Since Rejuran is an injection procedure, many people hesitate due to concerns about pain.
When the topic of pain comes up in the consultation room, I first address the preparation process rather than the pain itself. Preparation significantly influences the perceived pain.
The preparation process is generally as follows:
- Before the procedure, apply anesthetic cream thickly, not thinly.
- Allow sufficient time for the cream to penetrate to dull skin sensation.
- Immediately after the procedure, continue with soothing care such as cooling or LED to alleviate swelling and redness.
Applying the cream thickly can help reduce the stimulation transmitted to the skin.
(※ Immediately after the procedure, temporary swelling, redness, and discomfort may occur, and pain or bruising may appear at the injection site. These reactions vary depending on the individual's skin condition.)
Misunderstandings about how to manage pain are also common.
A typical belief is that the more painful the injection, the greater the effect, but the intensity of pain does not directly correlate with treatment satisfaction.
This point was specifically addressed in an article summarizing what to look at before pain, and if you have particularly high pain concerns, you may also find guidance on Rejuran HB pain helpful.


A few days after the procedure, soothe your skin this way
After Rejuran, the skin may temporarily become sensitive.
During this period, soothing and home care are as important as the procedure itself.
Avoiding irritating actions immediately after the procedure and following the home care routine advised by the medical staff can aid recovery.
Here's a breakdown of what to pay special attention to in summer home care, by period:
| Period | Points to check | Direction |
|---|---|---|
| Immediately after treatment | Swelling, redness, heat sensation | Soothe with cooling and calming care |
| A few days into recovery | Exposure to strong UV rays | Pay attention to UV protection |
| Subsequent care | Repeated exposure to air conditioning and heat | Continuously maintain moisturizing and barrier care |
(※ Treatment effects and recovery speed vary depending on individual skin condition, and appropriate home care methods also differ from person to person.)
Sometimes, people rely too much on soothing and regenerating products applied after treatment and miss the overall management direction. This aspect can be explored in an article summarizing common misconceptions about regenerating creams.
If you have any questions, we recommend consulting with your medical staff to confirm the appropriate direction for your condition.


When choosing a clinic, look for 'this' first
When choosing a Rejuran clinic, price and promotions are actually the last things to consider.
The first things to check are whether the environment allows for treatment plans tailored to individual skin conditions, and whether sufficient consultation and examination are conducted before the procedure.
We recommend checking if AI skin measurement or 1:1 consultation with medical staff is available.
In terms of pain management, how the anesthetic cream is applied and whether post-treatment soothing care is provided are also key points to check.
How comfortably the procedure is performed also contributes to satisfaction.
If you wish to broaden your criteria for choosing a dermatology clinic, an article summarizing the perspective of a dermatology clinic from the consultation room may also be helpful.
(※ The effects and reactions of Rejuran may vary depending on individual skin conditions, and the applicability of the treatment is determined through consultation and examination by medical staff.)
If you're curious whether it's suitable for you, click Chat for a consultation to comfortably check your skin condition first.

Frequently Asked Questions
What skin concerns can Rejuran help with?
Rejuran is known as a treatment that can help organize the skin's regenerative environment, restore weakened barriers, and improve the moisture retention of the dermal layer using PDRN components.
It can be considered by those experiencing summer oil-moisture imbalance or sensitivity and troubles due to a weakened barrier. However, the degree and duration of perceived change vary depending on individual skin condition.
Is Rejuran pain very severe?
Since it is an injection procedure, some people feel concerned about pain.
We try to reduce pain by applying anesthetic cream thickly before the procedure to dull sensation. The degree of pain varies depending on individual pain sensitivity and skin condition.
Is it possible to return to daily life immediately after the procedure?
Temporary swelling, redness, pain, and bruising may appear at the injection site. Combining cooling or LED soothing care immediately after the procedure can make the recovery process more comfortable.
Recovery period and return to daily life may vary depending on individual skin condition, so we recommend confirming with your medical staff through consultation.
How long do the effects last?
The degree and duration of perceived change vary depending on individual skin condition and lifestyle.
To maintain the effects for a long time, consistently continuing home care and barrier management after the procedure can be helpful.
For specific duration, we recommend confirming with medical staff through consultation tailored to your individual condition.
What preparation is needed before the procedure?
First, it is important to confirm a treatment plan tailored to your skin condition and treatment goals through sufficient consultation with medical staff.
Understanding your condition through AI skin measurement and then designing the direction can help in expecting satisfactory results.
We recommend that the applicability of the treatment be determined through examination and consultation with medical staff.
Recovery and Downtime
Rejuran is an injection procedure, so reactions such as swelling, redness, numbness, and mild bruising may appear at the injection site.
(※ These reactions usually subside within a few days, but the degree and duration vary depending on individual skin condition and pain sensitivity.)
Combining cooling or LED soothing care immediately after the procedure can make the recovery process more comfortable, and it is helpful to avoid strong irritants like saunas or excessive UV exposure for the first few days.
We recommend confirming the return to daily life with your medical staff through consultation.
How is the cost structured?
The cost of Rejuran cannot be stated as a single fixed number.
The structure varies depending on the skin condition confirmed by AI skin measurement, the scope and area of the treatment, the number of sessions, and whether post-treatment soothing and home care management are included.
Even with the same Rejuran, the approach differs according to skin type and purpose, so it is better to consider what is included in the plan rather than simply comparing prices.
We recommend receiving guidance on the exact cost suitable for you after examination and consultation.
Visit and Consultation Information
O.N Clinic is conveniently located near Sinnonhyeon Station and Gangnam Station, making it easy to schedule a visit.
For first-time visitors, making a reservation before your visit can facilitate consultation and AI skin measurement without waiting.
If you want to first check if Rejuran is suitable for your skin, feel free to inquire about your skin condition via chat consultation.
Author: Dr. Oh Seung-min (Chief Director, O.N Clinic; Graduated from Seoul National University College of Medicine; Academic Committee Chairman, Korean Society for Laser Dermatology and Hair). For more details on his background, please refer to Medical Staff Introduction. First Published: 2026-06-12 / Last Reviewed: 2026-08-15
This article is for general informational purposes only, and appropriate treatment and results may vary depending on individual conditions.